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Vinpocetine is a derivative of the alkaloid vincamine and it is found in small amounts in the seeds of periwinkle.
Vinpocetine is a powerful memory enhancer. It achieves this principally by facilitating cerebral metabolism and improving blood flow in the brain. It works by causing mild dilation of blood vessels, thereby allowing for increased cerebral blood flow, which results in increased oxygenation and glucose utilization.
This makes vinpocetine an ideal candidate not only for the improvement and prevention of certain disease processes in need of increased blood flow and oxygenation, but also for athletes who want to enhance their performance by increasing brain oxygenation, such as skiers, mountain climbers, and high-altitude hikers.
Improve memory, long- and short-term
Enhance alertness, awareness, and preparedness
Act as a neuroprotector
Prevent or reverse ischemic (lack of oxygen) damage to brain, muscle, liver
Diminish senile cerebral dysfunction
Improve Hearing Function
Prevent or relieve hearing loss due to various causes
Prevent or relieve tinnitus (ringing/buzzing in the ears)
Prevent or relieve vertigo (dizziness)
Improve Visual Function
Improve night vision
Improve wound healing of eyes due to burns
Prevent or relieve glaucoma
Prevent or improve age-related macular decline
Most studies showing positive benefits from vinpocetine have been done at amounts of 10 to 30 mg/day, and some at 40 mg/day. All studies done at 30 mg/day showed additional benefits compared with lesser daily amounts. Depending on your body chemistry, you could start with 10 mg/day and work up, or you could start with 30 mg/day.
Study of the effects of vinpocetin on cognitive functions
Vinpocetine, due its complex mechanism of action, improved significantly the cognitive functions, overall disease status and quality of life in patients with chronic cerebral hypoperfusion. As a result, vinpocetine treatment can be recommended for patients with mild cognitive impairment.
Memorial Sloan Kettering Cancer Center
"Vinpocetine also demonstrates anti-inflammatory effects by inhibiting tumor necrosis factor-alpha (TNF-α)-induced NF-κB activities"